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Here at Journalspotting headquarters we sacrificed our vitamin d levels and frisbee skills during the sunny month of May, and have compiled an episode that will get you up to scratch with what you missed while you were out sunbathing. In this months episode:

...Does a lower BP lower the risk of dementia?...(04:38)
Hughes, Diarmaid et al. “Association of Blood Pressure Lowering With Incident Dementia or Cognitive Impairment: A Systematic Review and Meta-analysis.” JAMA. doi:10.1001/jama.2020.4249


...When’s the right time to start dialysis in severe AKI?...(08:51)
Gaudry, Stéphane et al. “Delayed versus early initiation of renal replacement therapy for severe acute kidney injury: a systematic review and individual patient data meta-analysis of randomised clinical trials.” Lancet, doi:10.1016/S0140-

...Do I really need to find ice for an ammonia level?...(13:10)
Haj, Mona, and Don C Rockey. “Ammonia Levels Do Not Guide Clinical Management of Patients With Hepatic Encephalopathy Caused by Cirrhosis.” The American journal of gastroenterology. doi:10.14309/ajg.0000000000000343

...Is there a safer antiplatelet for the elderly?...(19:18)
Gimbel, Marieke et al. “Clopidogrel versus ticagrelor or prasugrel in patients aged 70 years or older with non-ST-elevation acute coronary syndrome.” Lancet. doi:10.1016/S0140-6736(20)30325-1

...How can we better serve our patients in care homes?...(23:21)
Alcorn, Gemma et al. “Care home residents who die in hospital: exploring factors, processes and experiences.” Age and ageing, doi:10.1093/ageing/afz174

...Are fancy lipid-lowering drugs all their cracked up to be?...(29:24)
Gencer, Baris et al. “Efficacy of Evolocumab on Cardiovascular Outcomes in Patients With Recent Myocardial Infarction: A Prespecified Secondary Analysis From the FOURIER Trial.” JAMA cardiology, doi:10.1001/jamacardio.2020.0882

...How significant is the wrong diagnosis?...
Newman-Toker, David E et al. “Rate of diagnostic errors and serious misdiagnosis-related harms for major vascular events, infections, and cancers: toward a national incidence estimate using the "Big Three".” Diagnosis (Berlin, Germany), doi:10.1515/dx-2019-0104

...Can you trust the EWS score?...
Gerry, Stephen et al. “Early warning scores for detecting deterioration in adult hospital patients: systematic review and critical appraisal of methodology.” BMJ. doi:10.1136/bmj.m1501

JOURNALBITES
Canadian Syncope Score
Opioids in dialysis patient
VTE guideline update
PDE-4 inhibitors and COPD

...Cannabis & Fungal Infections...
Benedict, Kaitlin et al. “Cannabis Use and Fungal Infections in a Commercially Insured Population.” Emerging infectious diseases. doi:10.3201/eid2606.191570