The general medicine podcast to keep you up to date.
We scour the journals so that you don’t have to.
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...Does a lower BP lower the risk of dementia?...(04:38)
Hughes, Diarmaid et al. “Association of Blood Pressure Lowering With Incident Dementia or Cognitive Impairment: A Systematic Review and Meta-analysis.” JAMA. doi:10.1001/jama.2020.4249
...When’s the right time to start dialysis in severe AKI?...(08:51)
Gaudry, Stéphane et al. “Delayed versus early initiation of renal replacement therapy for severe acute kidney injury: a systematic review and individual patient data meta-analysis of randomised clinical trials.” Lancet, doi:10.1016/S0140-
...Do I really need to find ice for an ammonia level?...(13:10)
Haj, Mona, and Don C Rockey. “Ammonia Levels Do Not Guide Clinical Management of Patients With Hepatic Encephalopathy Caused by Cirrhosis.” The American journal of gastroenterology. doi:10.14309/ajg.0000000000000343
...Is there a safer antiplatelet for the elderly?...(19:18)
Gimbel, Marieke et al. “Clopidogrel versus ticagrelor or prasugrel in patients aged 70 years or older with non-ST-elevation acute coronary syndrome.” Lancet. doi:10.1016/S0140-6736(20)30325-1
...How can we better serve our patients in care homes?...(23:21)
Alcorn, Gemma et al. “Care home residents who die in hospital: exploring factors, processes and experiences.” Age and ageing, doi:10.1093/ageing/afz174
...Are fancy lipid-lowering drugs all their cracked up to be?...(29:24)
Gencer, Baris et al. “Efficacy of Evolocumab on Cardiovascular Outcomes in Patients With Recent Myocardial Infarction: A Prespecified Secondary Analysis From the FOURIER Trial.” JAMA cardiology, doi:10.1001/jamacardio.2020.0882
...How significant is the wrong diagnosis?...
Newman-Toker, David E et al. “Rate of diagnostic errors and serious misdiagnosis-related harms for major vascular events, infections, and cancers: toward a national incidence estimate using the "Big Three".” Diagnosis (Berlin, Germany), doi:10.1515/dx-2019-0104
...Can you trust the EWS score?...
Gerry, Stephen et al. “Early warning scores for detecting deterioration in adult hospital patients: systematic review and critical appraisal of methodology.” BMJ. doi:10.1136/bmj.m1501
JOURNALBITES
Canadian Syncope Score
Opioids in dialysis patient
VTE guideline update
PDE-4 inhibitors and COPD
...Cannabis & Fungal Infections...
Benedict, Kaitlin et al. “Cannabis Use and Fungal Infections in a Commercially Insured Population.” Emerging infectious diseases. doi:10.3201/eid2606.191570