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In this month's episode...
(05:11)...Sepsis bundles, not greater than the sum of their parts?...
Baghdadi, Jonathan D et al. “Association of a Care Bundle for Early Sepsis Management With Mortality Among Patients With Hospital-Onset or Community-Onset Sepsis.” JAMA
(10:39)...Aspirin might prevent HCC (and preserve flowers?)
Simon, Tracey G et al. “Association of Aspirin with Hepatocellular Carcinoma and Liver-Related Mortality.” NEJM
(17:30)...CPAPathon: ACS/OSA/CO (there's a good anagram in there somewhere)...
Sánchez-de-la-Torre, Manuel et al. “Effect of OSA and its treatment with continuous positive airway pressure on the prevalence of cardiovascular events in patients with acute coronary syndrome (ISAACC study): a randomised controlled trial.” Lancet
Wimms, Kelly et al. "CPAP versus standard care for the treatment of people with mild obstructive sleep apnoea (MERGE): a multicentre, randomised controlled trial" Lancet
Turgut & Yavuz. "Comparison of non-invasive CPAP with mask use in carbon monoxide poisoning" AJEM
(27:52)...Diets and cardiovascular disease...
Ge, Long et al. “Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials.” BMJ
(37:17)...Does MRSA bacteremia need anything more than vancomycin ...
Tong, Steven Y C et al. “Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial.” JAMA
(40:43)...is your stethoscope spreading the next pandemic?...
Sukaina Ali Alali et. al "Community Hospital Stethoscope Cleaning Practices and Contamination Rates" AJIC
(44:24)...JOURNALBITES...
Benzo-resistant status epilepticus
Penicillin allergy decision rule
New anaphylaxis guidelines
SGLT2 inhibitors and heart failure
(50:07)...Medieval strains of m. leprae in the red squirrel...
Ploemacher, Thomas et al. “Reservoirs and transmission routes of leprosy; A systematic review.” PLoS neglected tropical diseases